Bunik, Victoria I: search on Z-Library

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1

Structure–function relationships in the 2-oxo acid dehydrogenase family: Substrate-specific signatures and functional predictions for the 2-oxoglutarate dehydrogenase-like proteins

Victoria I. Bunik, Dmitry Degtyarev

Journal:

Proteins: Structure, Function, and Bioinformatics

Year:

2008

Language:

english

File:

PDF, 2.36 MB

english, 2008

2

The multifaceted role of vitamin B 6 in cancer: Drosophila as a model system to investigate DNA damage

Contestabile, Roberto, di Salvo, Martino Luigi, Bunik, Victoria, Tramonti, Angela, VernÃ¬, Fiammetta

Journal:

Year:

2020

File:

PDF, 849 KB

2020

3

Phosphonate Analogs of 2-Oxoglutarate Perturb Metabolism and Gene Expression in Illuminated Arabidopsis Leaves

Araújo, Wagner L., Tohge, Takayuki, Nunes-Nesi, Adriano, Daloso, Danilo M., Nimick, Mhairi, Krahnert, Ina, Bunik, Victoria I., Moorhead, Greg B. G., Fernie, Alisdair R.

Journal:

Frontiers in Plant Science

Year:

2012

Language:

english

File:

PDF, 4.32 MB

english, 2012

4

The α-ketoglutarate-dehydrogenase complex

Gary E. Gibson, John P. Blass, M. Flint Beal, Victoria Bunik

Journal:

Molecular Neurobiology

Year:

2005

Language:

english

File:

PDF, 195 KB

english, 2005

5

Inhibition of select mitochondrial enzymes in PC12 cells exposed to S-(1,1,2,2-tetrafluoroethyl)-l-cysteine

Larry C.H. Park, Gary E. Gibson, Victoria Bunik, Arthur J.L. Cooper

Journal:

Biochemical Pharmacology

Year:

1999

Language:

english

File:

PDF, 459 KB

english, 1999

6

Inactivation of the 2-oxo acid dehydrogenase complexes upon generation of intrinsic radical species

Victoria I. Bunik, Christian Sievers

Journal:

Year:

2002

Language:

english

File:

PDF, 390 KB

english, 2002

7

Kinetic properties of the 2-oxoglutarate dehydrogenase complex from Azotobacter vinelandii : Evidence for the formation of a precatalytic complex with 2-oxoglutarate

Victoria Bunik, Adrie H. Westphal, Aart de Kok

Journal:

Year:

2000

Language:

english

File:

PDF, 751 KB

english, 2000

8

Characterization of thioredoxins by sodium dodecyl sulfate-slab gel electrophoresis and high performance capillary electrophoresis

Dr. Victoria Bunik, Alexandra Shoubnikova, Hans Bisswanger, Hartmut Follmann

Journal:

ELECTROPHORESIS

Year:

1997

Language:

english

File:

PDF, 558 KB

english, 1997

9

Increased catalytic performance of the 2-oxoacid dehydrogenase complexes in the presence of thioredoxin, a thiol–disulfide oxidoreductase

Journal:

Journal of Molecular Catalysis B: Enzymatic

Year:

2000

Language:

english

File:

PDF, 1.10 MB

english, 2000

10

Production of superoxide/hydrogen peroxide by the mitochondrial 2-oxoadipate dehydrogenase complex

Goncalves, Renata L.S., Bunik, Victoria I., Brand, Martin D.

Journal:

Free Radical Biology and Medicine

Year:

2016

Language:

english

File:

PDF, 1.23 MB

english, 2016

11

Hypoxic Adaptation of Mitochondrial Metabolism in Rat Cerebellum Decreases in Pregnancy

Graf, Anastasia, Trofimova, Lidia, Ksenofontov, Alexander, Baratova, Lyudmila, Bunik, Victoria

Journal:

Year:

2020

File:

PDF, 686 KB

2020

12

Synthetic regulators of the 2-oxoglutarate oxidative decarboxylation alleviate the glutamate excitotoxicity in cerebellar granule neurons

Maria S. Kabysheva, Tatiana P. Storozhevykh, Vsevolod G. Pinelis, Victoria I. Bunik

Journal:

Biochemical Pharmacology

Year:

2009

Language:

english

File:

PDF, 647 KB

english, 2009

13

Up-regulation of 2-oxoglutarate dehydrogenase as a stress response

Graf, Anastasia, Trofimova, Lidia, Loshinskaja, Alexandra, Mkrtchyan, Garik, Strokina, Anastasiia, Lovat, Maxim, Tylicky, Adam, Strumilo, Slawomir, Bettendorff, Lucien, Bunik, Victoria I.

Journal:

The International Journal of Biochemistry & Cell Biology

Year:

2013

Language:

english

File:

PDF, 1.03 MB

english, 2013

14

Benefits of Thiamin (Vitamin B1) Administration in Neurodegenerative Diseases may be Due to Both the Coenzyme and Non-coenzyme Roles of Thiamin

Bunik, Victoria I

Journal:

Journal of Alzheimer's Disease & Parkinsonism

Year:

2014

File:

PDF, 470 KB

2014

15

Activation of Mitochondrial 2-Oxoglutarate Dehydrogenase by Cocarboxylase in Human Lung Adenocarcinoma Cells A549 Is p53/p21-Dependent and Impairs Cellular Redox State, Mimicking the Cisplatin Action

Bunik, Victoria I., Aleshin, Vasily A., Zhou, Xiaoshan, Tabakov, Vyacheslav Yu., Karlsson, Anna

Journal:

International Journal of Molecular Sciences

Year:

2020

File:

PDF, 1.98 MB

2020

16

Role of 2-oxoglutarate dehydrogenase in brain pathologies involving glutamate neurotoxicity

Anastasia Graf, Maria Kabysheva, Eugeny Klimuk, Lidia Trofimova, Tatiana Dunaeva, Gregor Zündorf, Stefan Kahlert, Georg Reiser, Tatiana Storozhevykh, Vsevolod Pinelis, Natalia Sokolova, Victoria Bunik

Journal:

Journal of Molecular Catalysis B: Enzymatic

Year:

2009

Language:

english

File:

PDF, 667 KB

english, 2009

17

Advantages of formate dehydrogenase reaction for efficient NAD+ quantification in biological samples

Artiukhov, Artem V., Pometun, Anastasia A., Zubanova, Sofia A., Tishkov, Vladimir I., Bunik, Victoria I.

Journal:

Analytical Biochemistry

Year:

2020

File:

PDF, 678 KB

2020

18

Activation of Mitochondrial 2-Oxoacid Dehydrogenases by Thioredoxin

Bunik, Victoria, Follmann, Hartmut, Bisswanger, Hans

Journal:

Biological Chemistry

Year:

1997

Language:

english

File:

PDF, 1.35 MB

english, 1997

19

Conformational transitions in the active site of mycobacterial 2-oxoglutarate dehydrogenase upon binding phosphonate analogues of 2-oxoglutarate: From a Michaelis-like complex to ThDP adducts

Wagner, Tristan, Boyko, Alexandra, Alzari, Pedro M., Bunik, Victoria I., Bellinzoni, Marco

Journal:

Journal of Structural Biology

Year:

2019

Language:

english

File:

PDF, 1.87 MB

english, 2019

20

Interaction of thioredoxins with target proteins: Role of particular structural elements and electrostatic properties of thioredoxins in their interplay with 2-oxoacid dehydrogenase complexes

Victoria Bunik, Günter Raddatz, Hans Bisswanger, Stephane Lemaire, Yves Meyer, Jean-Pierre Jacquot

Journal:

Protein Science

Year:

1999

Language:

english

File:

PDF, 1.11 MB

english, 1999

21

Thiamin-dependent enzymes: new perspectives from the interface between chemistry and biology

Bunik, Victoria I.

Journal:

Year:

2013

Language:

english

File:

PDF, 56 KB

english, 2013

22

Positive correlation between rat brain glutamate concentrations and mitochondrial 2-oxoglutarate dehydrogenase activity

Mkrtchyan, Garik V., Graf, Anastasia, Trofimova, Lidia, Ksenofontov, Alexander, Baratova, Ludmila, Bunik, Victoria

Journal:

Analytical Biochemistry

Year:

2018

Language:

english

File:

PDF, 4.89 MB

english, 2018

23

Diurnal regulation of the function of the rat brain glutamate dehydrogenase by acetylation and its dependence on thiamine administration

Aleshin, Vasily A, V Mkrtchyan, Garik, Kaehne, Thilo, V Graf, Anastasia, V Maslova, Maria, I Bunik, Victoria

Journal:

Journal of Neurochemistry

Year:

2019

File:

PDF, 3.45 MB

2019

24

Inhibitors of the α-ketoglutarate dehydrogenase complex alter [1-13C]glucose and [U-13C]glutamate metabolism in cerebellar granule neurons

Sónia Sá Santos, Gary E. Gibson, Arthur J.L. Cooper, Travis T. Denton, Charles M. Thompson, Victoria I. Bunik, Paula M. Alves, Ursula Sonnewald

Journal:

Journal of Neuroscience Research

Year:

2006

Language:

english

File:

PDF, 378 KB

english, 2006

25

Inhibition of 2-Oxoglutarate Dehydrogenase in Potato Tuber Suggests the Enzyme Is Limiting for Respiration and Confirms Its Importance in Nitrogen Assimilation

Wagner L. Araújo, Adriano Nunes-Nesi, Sandra Trenkamp, Victoria I. Bunik and Alisdair R. Fernie

Journal:

PLANT PHYSIOLOGY

Year:

2008

Language:

english

File:

PDF, 2.56 MB

english, 2008

26

Chronic alcoholism in rats induces a compensatory response, preserving brain thiamine diphosphate, but the brain 2-oxo acid dehydrogenases are inactivated despite unchanged coenzyme levels

Yulia M. Parkhomenko, Pavel A. Kudryavtsev, Svetlana Yu. Pylypchuk, Lilia I. Chekhivska, Svetlana P. Stepanenko, Andrej A. Sergiichuk, Victoria I. Bunik

Journal:

Journal of Neurochemistry

Year:

2011

Language:

english

File:

PDF, 305 KB

english, 2011

27

Metabolic control exerted by the 2-oxoglutarate dehydrogenase reaction: a cross-kingdom comparison of the crossroad between energy production and nitrogen assimilation

Bunik, Victoria I., Fernie, Alisdair R.

Journal:

Biochemical Journal

Year:

2009

Language:

english

File:

PDF, 633 KB

english, 2009

28

Enzyme-Catalyzed Side Reactions with Molecular Oxygen may Contribute to Cell Signaling and Neurodegenerative Diseases

Victoria I. Bunik, John V. Schloss, John T. Pinto, Gary E. Gibson, Arthur J. L. Cooper

Journal:

Neurochemical Research

Year:

2007

Language:

english

File:

PDF, 451 KB

english, 2007

29

A novel variant m.641A>T in the mitochondrial MT-TF gene is associated with epileptic encephalopathy in adolescent

Itkis, Yulia, Krylova, Tatiana, Pechatnikova, Natalia L., De Grassi, Anna, Tabakov, Vyacheslav Yu., Pierri, Ciro Leo, Aleshin, Vasiliy, Boyko, Aleksandra, Bunik, Victoria I., Zakharova, Ekaterina Yu.

Journal:

Year:

2019

Language:

english

File:

PDF, 1.34 MB

english, 2019

30

Brain pyruvate and 2-oxoglutarate dehydrogenase complexes are mitochondrial targets of the CoA ester of the Refsum disease marker phytanic acid

Victoria I. Bunik, Günter Raddatz, Ronald J.A. Wanders, Georg Reiser

Journal:

Year:

2006

Language:

english

File:

PDF, 331 KB

english, 2006

31

On the role of the mitochondrial 2-oxoglutarate dehydrogenase complex in amino acid metabolism

AraÃºjo, Wagner L., Trofimova, Lidia, Mkrtchyan, Garik, Steinhauser, Dirk, Krall, Leonard, Graf, Anastasia, Fernie, Alisdair R., Bunik, Victoria I.

Journal:

Year:

2013

Language:

english

File:

PDF, 728 KB

english, 2013

32

Multiple Forms of Glutamate Dehydrogenase in Animals: Structural Determinants and Physiological Implications

Bunik, Victoria, Artiukhov, Artem, Aleshin, Vasily, Mkrtchyan, Garik

Journal:

Year:

2016

Language:

english

File:

PDF, 3.24 MB

english, 2016

33

2-Oxo acid dehydrogenase complexes of multicellular organisms : Regulatory aspects

Victoria I. Bunik

Journal:

Year:

2003

Language:

english

File:

PDF, 55 KB

english, 2003

34

REDOX-DRIVEN SIGNALING: 2-OXO ACID DEHYDROGENASE COMPLEXES AS SENSORS AND TRANSMITTERS OF METABOLIC IMBALANCE

Bunik, Victoria

Journal:

Antioxidants & Redox Signaling

Year:

2018

Language:

english

File:

PDF, 1.51 MB

english, 2018

35

Homology Modelling of a Newly Discovered Thioredoxin Protein and Analysis of the Force Field and Electrostatic Properties

Günter Raddatz, Victoria I. Bunik, Thomas Scior, Hans Bisswanger

Journal:

Journal of Molecular Modeling

Year:

1997

Language:

english

File:

PDF, 133 KB

english, 1997

36

The RNA-binding protein HuR is essential for the B cell antibody response

Diaz-Muñoz, Manuel D, Bell, Sarah E, Fairfax, Kirsten, Monzon-Casanova, Elisa, Cunningham, Adam F, Gonzalez-Porta, Mar, Andrews, Simon R, Bunik, Victoria I, Zarnack, Kathi, Curk, Tomaž, Heggermont, Wa

Journal:

Nature Immunology

Year:

2015

Language:

english

File:

PDF, 3.13 MB

english, 2015

37

2-Oxo acid dehydrogenase complexes in redox regulation : Role of the lipoate residues and thioredoxin

Victoria I. Bunik

Journal:

Year:

2003

Language:

english

File:

PDF, 236 KB

english, 2003

38

Translating Enzymology into Metabolic Regulation: The Case of the 2- Oxoglutarate Dehydrogenase Multienzyme Complex

I. Bunik, Victoria, Raddatz, Guenter, Strumilo, Slawomir

Journal:

Current Chemical Biology

Year:

2013

Language:

english

File:

PDF, 1.85 MB

english, 2013

39

Structural determinants for the efficient and specific interaction of thioredoxin with 2-oxoacid dehydrogenase complexes

Guenter Raddatz, Volker Kruft, Victoria Bunik

Journal:

Applied Biochemistry and Biotechnology

Year:

2000

Language:

english

File:

PDF, 431 KB

english, 2000

40

Molecular mechanisms of the non-coenzyme action of thiamin in brain: biochemical, structural and pathway analysis

Mkrtchyan, Garik, Aleshin, Vasily, Parkhomenko, Yulia, Kaehne, Thilo, Luigi Di Salvo, Martino, Parroni, Alessia, Contestabile, Roberto, Vovk, Andrey, Bettendorff, Lucien, Bunik, Victoria

Journal:

Scientific Reports

Year:

2015

Language:

english

File:

PDF, 3.48 MB

english, 2015

41

Tricarboxylic Acid Cycle Activity Regulates Tomato Root Growth via Effects on Secondary Cell Wall Production

Margaretha J. van der Merwe, Sonia Osorio, Wagner L. Araújo, Ilse Balbo, Adriano Nunes-Nesi, Eugenia Maximova, Fernando Carrari, Victoria I. Bunik, Staffan Persson and Alisdair R. Fernie

Journal:

PLANT PHYSIOLOGY

Year:

2010

Language:

english

File:

PDF, 2.10 MB

english, 2010

42

Thioredoxin reduction dependent on α-ketoacid oxidation by α-ketoacid dehydrogenase complexes

Victoria Bunik, Hartmut Follmann

Journal:

Year:

1993

Language:

english

File:

PDF, 436 KB

english, 1993

43

Succinyl phosphonate, a protector of the 2-oxoglutarate dehydrogenase complex, corrects behavioral impairments in rats exposed to hypoxia or ethanol

Bunik, Victoria I., Lovat, Maxim, Groznaya, Alexandra, Graf, Anastasia, Dunaeva, Tatiana, Trofimova, Lidia, Sokolova, Natalia

Journal:

Alzheimer's & Dementia

Year:

2009

Language:

english

File:

PDF, 59 KB

english, 2009

44

Mitochondrial Impairment May Increase Cellular NAD(P)H: Resazurin Oxidoreductase Activity, Perturbing the NAD(P)H-Based Viability Assays

Aleshin, Vasily, Artiukhov, Artem, Oppermann, Henry, Kazantsev, Alexey, Lukashev, Nikolay, Bunik, Victoria

Journal:

Year:

2015

Language:

english

File:

PDF, 2.55 MB

english, 2015

45

Novel isoenzyme of 2-oxoglutarate dehydrogenase is identified in brain, but not in heart

Victoria Bunik, Thilo Kaehne, Dmitry Degtyarev, Tatiana Shcherbakova, Georg Reiser

Journal:

Year:

2008

Language:

english

File:

PDF, 379 KB

english, 2008

46

Thiamin diphosphate-dependent enzymes: from enzymology to metabolic regulation, drug design and disease models

Bunik, Victoria I., Tylicki, Adam, Lukashev, Nikolay V.

Journal:

Year:

2013

Language:

english

File:

PDF, 776 KB

english, 2013

47

Phosphono Analogues of 2-Oxoglutarate Protect Cerebellar Granule Neurons upon Glutamate Excitotoxicity

Victoria I. Bunik, Maria S. Kabysheva, Eugeny I. Klimuk, Tatiana P. Storozhevykh, Vsevolod G. Pinelis

Journal:

Annals of the New York Academy of Sciences

Year:

2009

Language:

english

File:

PDF, 310 KB

english, 2009

48

Phosphonate Analogues of α-Ketoglutarate Inhibit the Activity of the α-Ketoglutarate Dehydrogenase Complex Isolated from Brain and in Cultured Cells †

Bunik, Victoria I., Denton, Travis T., Xu, Hui, Thompson, Charles M., Cooper, Arthur J. L., Gibson, Gary E.

Journal:

Year:

2005

Language:

english

File:

PDF, 133 KB

english, 2005

49

Generation of superoxide and hydrogen peroxide by side reactions of mitochondrial 2-oxoacid dehydrogenase complexes in isolation and in cells

Bunik, Victoria I., Brand, Martin D.

Journal:

Biological Chemistry

Year:

2017

Language:

english

File:

PDF, 794 KB

english, 2017

50

Molecular characterization of pyridoxine 5â²-phosphate oxidase and its pathogenic forms associated with neonatal epileptic encephalopathy

Barile, Anna, NoguÃ©s, Isabel, di Salvo, Martino L., Bunik, Victoria, Contestabile, Roberto, Tramonti, Angela

Journal:

Scientific Reports

Year:

2020

File:

PDF, 3.47 MB

2020

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